Avastin 100mg Injection

Product Description

AVASTIN 100MG contains Bevacizumab which belongs to a group of medicines called antiangiogenic agents. It is indicated to treat metastatic colorectal cancer, first-line non-squamous non small cell lung cancer, recurrent glioblastoma (GBM), metastatic renal cell carcinoma, persistent, recurrent, or metastatic cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer and hepatocellular carcinoma.\n\nBevacizumab is a humanized monoclonal IgG1 antibody which contains human framework regions and murine complementarity determining regions. This binds VEGF and prevents the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. This interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in invitro models of angiogenesis. Bevacizumab reduces microvascular growth and inhibition of metastatic disease progression.